Objective:To conduct such a study on TSS downstream of mitral stenosis using a finite element model of two dimensions combined with Doppler echocardiography in human beings.Method:Non-invasive Doppler echocar-diography was used to pick up in real-time way two dimensional images of left cardiac cavity and average ve-locities of left atrium and left ven tricle as boundary conditions,we conducted a computational study of TSS downstream of mitral valve in a group of patients with mitral stenosis during their follow-up using the finite el-ement method.Result:There was a significant difference with respect of TSS and Wilkins grade of valvular le-sion between the twice of follow-up(P<0.05),and the two items correlated with each other(r:0.80-0.82).Be-sides,however the extent of valvular lesion and stenosis is,TSS in the centerline locations is lower than that in the boundary locations.The maximul number of the former is less than80N/m 2 .Our results showed coincident with those of previousre searches.Conclusion:There is an obvious relationship between TSS downstream of mi tral stenosis and the aggravation of valvular lesion.The description of TSS and velocity in the local and total flow field of valve with finite element method is quite detailed and intact.So the combination of the two methods makes the quantitative study of TSS in the flow field of cardiac valve to be comprehensive and accurate.