Objective:To investigate the curative effects of optimized form of Duangudan on fracture healing. Method: 64 cases of rapine distal radial fracture models were randomized into 4 groups, blank control group (normal fracture healing without treatment) group of conventional form of Duangudan, group of emplastrum form prepared from conventional extractum, group of emplastrum form prepared from optimized extractum. Meanwhile, eight cases with intact radii were sacrificed from normal control. They were sacrificed at 2nd and 4th week in batches. All involved radii were harvested for biomechanical observation (three-point bending test). Results: At the end of 2nd week, in order of curative effect, the groups were ranked as follows, group of emplastrum form prepared from optimized extractum, goup of previous form of Duangudan, an blank control group. At the end of 4th week, the rank remained all the same as that at the end of 2nd week. There was significant difference in biomechanical test between the emplastrum form prepared from optimized extractum and blank control at both ends of 2nd and 4th week. Conclusion:The emplastrum form prepared from optimized extractum was superior to the conventional form in enhancing fracture healing.