Objective To investigate injury mechanisms of human calcaneus under impact loading in order to provide scientific references to clinical serice including operation, fixation, and rehabilitation. Methods An experimental model of calcacalcaneal dynamics was established using twenty fresh human cadaveric calcaneus for impact loading test. Results Based on the impact experiment results, the dynamic response of the human calcaneus to the impact loading at high crash rate was analyzed, the characteristics of the human calcaneal impact dynamics were obtained, and a typical compressive strain was found to produce calcaneal crushing fracture. Coclusion The testing results suggested the importance to establish classifications of human calcaneal injuries, including the impact injury mechanisms,the quantification of biomechanical response to the impact loading, the viscoelastic properties of the bone, the determination of threshold for the maximal impact loading, and the measures for injury prevention.