Objective To explore the effect of restraint system misuse on head-neck injuries for rear occupant of 6-year-old children in frontal impact crashes. Methods Based on the previously validated 6-year-old child occupant finite element model, in terms of ECE R44 testing regulations, the impact crash under right and wrong use of restraint system was simulated in Pam-Crash software. Results The force and moment of the neck were the minimum by merely using booster seat, but the maximum intracranial pressure, the maximum stress and the maximum principal strain were larger than their damage threshold and would cause fatal brain damage in child head. The only use of adult safety belt would cause more serious damage in child neck with larger force and moment. Conclusions Two ways of misusing the restraint system would aggravate head-neck injuries of the 6-year-old child. The proper use of the restraint system can provide the best protective effect for head and neck of the 6-year-old child occupant.