In recent years, the effects of the neuro-biomechanical ergogenic technology on improving and enhancing human function and physical movement performance have widely attracted certain attentions. This review summarized the recent achievements in the effects of non-invasive brain stimulation (NIBS) and biomechanical ergogenic technology based on sports equipment on human physical performance, and further explored the possible mechanisms for improving and promoting human physical performance. The obtained preliminary evidence based on animal experiments and biomechanical researches on neuromotor control under multi-joint movement were also summarized, so as to explain the coordinated development of human function enhancement at cerebral cortex regulation and neuromuscular coordinated control levels, and interpret its integration with sports equipment. This review ultimately provided certain references for the future frontier development and research position of neuro-biomechanics and human sports biomechanics.