Objective Based on the existing pneumoperitoneum device, a new suspension system for minimally invasive surgery was designed under the condition of low pressure, ao as to expose more surgical vision and facilitate the smooth operation.Methods Structure design of the suspension system was completed with Solidworks software. Based on the finite element simulation analysis technology, the effects of four different clamp materials, i.e. medical stainless steel, Ti6Al4V, Ti6Al7Nb and pure titanium, and three different mid-plane structure materials, i.e. nylon (PA6), polyester and polypropylene (PP), on performance of the suspension system were studied. Results In the process of clamping tissue by clamps with four different materials, the tissue deformation was lower. The gripped tissue did not slip out of the clamp. The stress of the clamp and its holding tissues were the lowest when the medical stainless steel material was selected. For the material of the mid-plane structure, when polyester was selected, the mid-plane structure would be destroyed under external loading in working process of the suspension system. When PP material was selected, the mid-plane structure would have the largest deformation, which was not conducive to the clinical operation.Conclusions The best material for clamp is medical stainless steel. It is not suitable to choose polyester as the material of the mid-plane structure, and choosing PA6 as the material of the mid-plane structure is the best.